The Effects of Movement Profile on Biochemical Markers of Internal and External Training Load Response to Controlled High-Intensity Exercise in Young, Physically Active Femal
Undergraduates: Kathleen Connell, Barnett Frank, PhD.
Faculty Advisor: Darin Padua
Department: Exercise & Sport Science
Background: An athlete¿¿¿s movement patterns directly influence the amount of stress placed on the body, therefore either increasing or decreasing injury risk. Purpose: The purpose of this study was to evaluate a link between biomechanics and physiological training load responses to high-intensity exercise (HIEE). Methods: Individuals were classified as ¿¿¿high injury risk¿¿¿ (LOW) and ¿¿¿low injury risk¿¿¿ (HIGH). Blood samples were collected pre and post-exercise. Serum cortisol, creatine kinase (CK-MM), and serum cartilage protein (sCOMP) were levels were evaluated using 2x2 mixed-model ANOVAs and 95% confidence intervals. Results: We observed a group-by-time interaction for CK-MM; LOW experienced a significantly greater increase (pre: 14.88 [7.62, 22.15] ng/ml, post: 20.14 [10.19, 30.09] ng/ml) in CK-MM when compared to HIGH (pre: 7.26 [6.64, 7.87] ng/ml, post: 7.73 [6.81,8.66] ng/ml). HIGH (205.08 [154.49, 255.68] ng/ml) exhibited significantly (F1,38=10.81, p<0.05) higher serum cortisol compared to LOW (128.92 [80.31, 177.53] ng/ml). Both groups experienced a significant increase (F1,39=4.39, p<0.05) in sCOMP in response to HIEE (pre: 457.04 [408.23, 505.84] ng/ml, post: 507.15 [451.90, 562.40] ng/ml). Conclusions: Individuals with HIGH exhibit higher overall stress levels (cortisol). Individuals with LOW load muscle tissue during exercise to a greater extent than individuals with HIGH, potentially offloading inert tissue that may not be resilient to higher mechanical stresses.