Comprehensive Nanoparticle Imaging via PRINT (2013)

Undergraduates: Sarika Mendu, John Fain

Faculty Advisor: Joseph DeSimone
Department: Business Administration

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The range of emission and defined physical properties of quantum dots allow for a variety of imaging applications both in-vitro and in-vivo. The PRINT (Particle Replication in Non-Wetting Templates) technique, a process developed by the DeSimone laboratories, is marked by its ability to exercise extreme control over the size and shape of produced particles. My research proves the successful encapsulation of quantum dots within PRINT particles during fabrication. Quantum dot encapsulated PRINT particles were easily identified within urinary epithelial cells via fluorescence microscopy. Overall, the recorded long term stability of quantum dots within PRINT particles represents widespread bio-imaging applications including tracking in animal studies.