Associations Between Carotid-Femoral and Brachial-Femoral Pulse Wave Velocity with Sleeping Regularity in College Based Young Adults (2024)
Undergraduates: Paul Ahern, Jake Diana, Dr. Erik Hanson.
Faculty Advisor: Zachary Kerr
Department: Exercise Sports Science
Cardiovascular disease (CVD) is the leading cause of mortality globally. Sleep is intrinsically related to health in humans. Lack of sleep time, quality, and consistency_x000D_
have been linked to increasing risk of CVD. Pulse wave velocity is a proxy of arterial stiffness. Arterial stiffness is indicative of _x000D_
blood vessel health and aging. Sleep irregularity is associated with higher risk of CVD in older adults, and is associated with future predictors of CVD like _x000D_
inflammation, microvascular dysfunction, and adiposity in younger adults. The relationship between sleep regularity and pulse wave velocity has not been _x000D_
thoroughly investigated. _x000D_
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In an initial visit We examined cardiometabolic profiles in 105 participants, while also tracking various other measures for the following 7 days. _x000D_
We used the Vicorder oscillometry system to measure pulse wave velocity and used the SleepScoreMax device to measure sleep. We performed a _x000D_
multiple linear regression analysis using R-studio programming software. Sleep regularity as measured via three different calculations served as our _x000D_
exposure and two different measures of pulse wave velocity served as our outcome._x000D_
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Our regression analysis did not yield a significant relationship in any of our models. None of our beta coefficients were prominent enough to suggest practical._x000D_
use in a clinical setting. _x000D_
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Further investigation is needed in order to establish a relationship between these two variables. If performing this analysis again refinement of _x000D_
protocol is recommended.