Research Assistant – Pathology and Laboratory Medicine
We study how the NuRD complex contributes to the silencing of fetal hemoglobin. My lab uses a combination of structural biology, biophysics, and tissue culture assays to understand how proteins bind to one another and to DNA. Our goal is to develop inhibitors of this complex as a potential therapy for blood disorders (sickle cell anemia and beta thalassemia) as well as acute leukemia.
The student will be involved in protein purification, binding assays using fluorescence polarization and ITC, as well as tissue culture experiments using BRET. As they gain experience, they will have an opportunity to take ownership of a project. Applicants should submit a resume and application letter.